Synthesis And Biological Activity Of Aminopyrimidine Derivatives

Abstract

Heterocyclic compounds are useful in medicinal field. Heterocyclic compound with pyrimidine, pyrazole, quinine etc. nucleus is very importance for the biological activity. In presence study, we have synthesized various pyrimidines by reaction between chalcones and Guanidine in the presence of sodium hydroxide as the base. Antimicrobial activity of all the synthesized compounds were perform against gram +ve and gram -ve bacteria. All synthesized compounds were done by ¹H NMR, ¹³C NMR, IR, MASS techniques.